MSM (methylsulfonylmethane), an organosulfur compound, exists naturally in some plants/animals. It comes from the sulfur cycle, entering fruits, vegetables and grains via soil absorption.

It can also be made by oxidizing dimethyl sulfoxide (DMSO). Studies confirm synthetic MSM matches natural MSM in structure and safety, while making it easier to hit recommended doses.

This helps develop nutritional supplements, letting consumers get sulfur nutrients conveniently—no need to rely on single natural foods—and boosts MSM use in health. 

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